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Article

The effect of shingles vaccination at different stages

of the dementia disease course

Graphical abstract

Highlights

•

Herpes zoster vaccination reduced dementia diagnosis in

our prior natural experiments

•

Here, we ﬁnd a lower occurrence of MCI and dementia

deaths among dementia patients

•

Herpes zoster vaccination appears to act along the entire

clinical course of dementia

•

This study’s approach avoids the common confounding

concerns of observational data

Authors

Min Xie, Markus Eyting,

Christian Bommer, Haroon Ahmed,

Pascal Geldsetzer

Correspondence

pgeldsetzer@stanford.edu

In brief

A natural experiment found that herpes

zoster vaccination reduced the

occurrence of mild cognitive impairment

and deaths due to dementia, indicating

that the vaccine may slow the

progression of dementia throughout its

clinical disease course.

Xie et al., 2025, Cell 188, 1–16

https://doi.org/10.1016/j.cell.2025.11.007

Article

The effect of shingles vaccination at different

stages of the dementia disease course

Min Xie,

1,2

Markus Eyting,

2,3,4

Christian Bommer,

Haroon Ahmed,

and Pascal Geldsetzer

2,6,7,8,9,

Heidelberg Institute of Global Health, Heidelberg University Hospital, 69120 Heidelberg, Germany

Division of Primary Care and Population Health, Department of Medicine, Stanford University, Stanford, CA 94305, USA

Faculty of Law and Economics, Johannes Gutenberg University Mainz, 55122 Mainz, Germany

Leibniz Institute for Financial Research SAFE, 60323 Frankfurt am Main, Germany

Division of Population Medicine, School of Medicine, Cardiff University, Cardiff CF14 4YS, UK

The Phil and Penny Knight Initiative for Brain Resilience at the Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA

Stanford Center for Digital Health, Stanford University, Stanford, CA 94305, USA

Biohub, San Francisco, CA 94158, USA

Lead contact

*Correspondence: pgeldsetzer@stanford.edu

https://doi.org/10.1016/j.cell.2025.11.007

SUMMARY

Using natural experiments, we have previously reported that live-attenuated herpes zoster (HZ) vaccination

appears to have prevented or delayed dementia diagnoses in both Wales and Australia. Here, we ﬁnd that HZ

vaccination also reduces mild cognitive impairment diagnoses and, among patients living with dementia,

deaths due to dementia. Exploratory analyses suggest that the effects are not driven by a speciﬁc dementia

type. Our approach takes advantage of the fact that individuals who had their eightieth birthday just after the

start date of the HZ vaccination program in Wales were eligible for the vaccine for 1 year, whereas those who

had their eightieth birthday just before were ineligible and remained ineligible for life. The key strength of our

natural experiments is that these comparison groups should be similar in all characteristics except for a min-

ute difference in age. Our ﬁndings suggest that live-attenuated HZ vaccination prevents or delays mild cogni-

tive impairment and dementia and slows the disease course among those already living with dementia.

INTRODUCTION

Given the key role of neuroinﬂammation in the development and

progression of dementia,

it is conceivable that neurotropic vi-

ruses could be a factor that causes or accelerates the dementia

disease process. Neurotropic herpesviruses have thus far

received the greatest research attention in this regard,

2–4

partly

because they remain latent for life in the nervous system after pri-

mary infection, are more likely to reactivate with increasing age,

and can cause encephalitis.

Recently, several ﬁndings have

further spurred interest in neurotropic herpesviruses, including

the observation that they can seed β-amyloid in mice

and in-

crease tau phosphorylation in human brain organoids

and that

the Epstein-Barr virus appears to be a causative factor in the

development of multiple sclerosis.

Clinical and subclinical reactivations of the neurotropic

herpesvirus (the varicella zoster virus) that causes chickenpox

and shingles may constitute a chronic immune stressor that

drives inﬂammatory pathways in both the peripheral and central

nervous system, interfering with neuroimmune homeostasis in

older age.

The varicella zoster virus has also recently been

linked to amyloid deposition and aggregation of tau proteins,

as well as cerebrovascular disease that resembles the patterns

commonly seen in Alzheimer’s disease, such as small- to

large-vessel disease, ischemia, infarction, and hemorrhage.

11–16

Reducing clinical and subclinical reactivations of the virus

through herpes zoster (HZ) vaccination might thus have a bene-

ﬁcial impact on the development or progression of dementia, as

well as neuroimmune health and cognitive reserve in older age

more broadly. Moreover, as has been detailed recently else-

where,

it is possible that HZ vaccination, and potentially vacci-

nations in older age more generally, act on the dementia disease

process through a pathogen-independent immune mechanism.

Such an effect might counteract immunosenescence

17,18

and

would add to the growing body of evidence suggesting that vac-

cines frequently have broader health beneﬁts beyond their in-

tended target.

19–22

Of importance with respect to this present

study, these beneﬁcial off-target effects have often been found

to be far stronger among female than male individuals,

well as for live-attenuated rather than other types of

vaccines.

19–21,23

In a recent study,

we were able to take advantage of a unique

quasi-randomization in Wales to provide evidence of the effect of

HZ vaccination on new dementia diagnoses that is more likely to

be causal than the previously existing associational evidence.

This opportunity arose because the UK National Health Service

OPEN ACCESS

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

Please cite this article in press as: Xie et al., The effect of shingles vaccination at different stages of the dementia disease course, Cell (2025),

https://doi.org/10.1016/j.cell.2025.11.007

rolled out the live-attenuated HZ vaccine (Zostavax, Merck) us-

ing strict date-of-birth-based eligibility rules.

These rules re-

sulted in an increase in the probability of ever receiving the HZ

vaccine of almost 50 percentage points between individuals

who differed in age by merely a week across the date-of-birth-

based eligibility threshold for the vaccination program. We thus

had the opportunity to compare dementia incidence between

eligible and ineligible groups of individuals who were not ex-

pected to differ in their characteristics other than a difference

in age of merely a few weeks and a large difference in ever having

received the HZ vaccine. We found that HZ vaccination averted

an estimated one in ﬁve new dementia diagnoses over a 7-year

follow-up period. Crucially, unlike the previously existing associ-

ational evidence,

26–35

this study is not subject to the fundamental

concern in associational studies that those who opt to be vacci-

nated differ from those who do not in a variety of characteristics

that are difﬁcult to measure.

Most recently, taking advantage of

a similar date-of-birth-based rollout of HZ vaccination in

Australia, we have shown that this protective effect for new diag-

noses of dementia from live-attenuated HZ vaccination also ap-

pears to exist in the Australian population.

To guide further research in this area and, ultimately, inform

appropriate clinical care, it is critical to understand at which

stage of the disease course of dementia HZ vaccination has its

beneﬁt. Our previous analyses in Wales and Australia have left

this question unanswered. The aims of this study, therefore,

were 2-fold: to determine the effect of HZ vaccination on (1)

new diagnoses of mild cognitive impairment (MCI) among indi-

viduals without any record of cognitive impairment and (2)

deaths due to dementia among individuals living with dementia.

In the absence of more widespread testing for β-amyloid and tau

pathology during the study period (2013–2022), these two aims

represent the two opposite ends of the disease course of de-

mentia (considering the limitations in ascertaining different dis-

ease stages in electronic health record data). Here, we report a

large beneﬁcial effect from live-attenuated HZ vaccination for

both aims, suggesting that the vaccine appears to act across

the entire clinical disease course of dementia.

RESULTS

Sample characteristics

We used the Secure Anonymised Information Linkage (SAIL) da-

tabank.

Our dataset, which consisted of electronic health re-

cord data from approximately 80% of Wales’s primary care

practices,

was linked by SAIL to hospital-based care data as

well as death certiﬁcate data (Table 1). Our dataset consisted

of 304,940 individuals born between September 1, 1925, and

September 1, 1942, who were alive and residing in Wales as of

September 1, 2013. Of these individuals, 282,557 did not have

a record of any cognitive impairment prior to September 1,

2013, and were thus included in our study cohort for analyzing

the effect of HZ vaccination on MCI. Our study cohort for

analyzing the effect of HZ vaccination on deaths due to dementia

consisted of the 14,350 individuals in our dataset who had

received a diagnosis of dementia prior to September 1, 2013.

The sample characteristics of each of these two cohorts are

shown in Table 2.

A 1-week difference in age led to a large difference in HZ

vaccination uptake

We analyzed our data using a regression discontinuity design,

which is a well-established causal effect estimation technique

that is guided by the expectation that individuals born just on

either side of the date-of-birth eligibility threshold for HZ vacci-

nation likely are similar to each other except for their probability

of receiving the HZ vaccine.

41–43

In both of our study cohorts, a

1-week difference in age across the September 2, 1933, date-of-

birth eligibility threshold resulted in a large difference in the

probability of ever receiving the HZ vaccination (Figures 1 and

S10). Speciﬁcally, among individuals without any record of

cognitive impairment prior to the start of the HZ vaccination pro-

gram, being born 1 week after September 2, 1933, and thus be-

ing eligible for HZ vaccination, led to an abrupt increase in the

probability of ever receiving the HZ vaccination from 0.0% to

45.9% (p < 0.001). The corresponding abrupt increase among

patients living with dementia on the start date of the HZ vaccina-

tion program was from 0.0% to 28.7% (p < 0.001). Thus, as ex-

pected, in both of our study cohorts, the eligibility rules of the HZ

vaccination program created comparison groups born just on

either side of the September 2, 1933, date-of-birth threshold

who (after ﬂexibly controlling for age) were likely similar to each

other except for a large difference in the probability of receiving

the HZ vaccination.

Prior to the start date of the HZ vaccination program, there

were no signiﬁcant differences at the September 2, 1933, date-

of-birth threshold in the uptake of preventive health services,

the prevalence of any of the ten most common causes of

disability-adjusted life years (DALYs) and mortality among adults

aged 70+ years in Wales (except ischemic heart disease among

those living with dementia at program start),

or in the occur-

rence of HZ, diagnoses of MCI, and deaths due to dementia

(Figure S1).

A protective effect of HZ vaccination on new diagnoses

of MCI

To determine the effect of being eligible for HZ vaccination on our

outcomes, our analytical strategy focused on comparing individ-

uals who were not eligible for the HZ vaccine because they

turned 80 years of age immediately before the program’s start

date with those who were eligible because they turned 80 years

of age immediately after the start date. Following standard

regression discontinuity methods,

41,42

we estimated the effect

of actually receiving the vaccine (rather than merely being

eligible) using a two-stage least-squares regression. This

approach divides the size of the sudden change in the outcome

at the date-of-birth eligibility cutoff by the size of the sudden

change in vaccine uptake at that same cutoff. As a result, the

fact that not everyone who was eligible actually received the vac-

cine does not introduce bias into our analysis.

Among our study cohort of individuals without any record of

cognitive impairment prior to the start date of the HZ vaccination

program, 20,712 (7.3%) were newly diagnosed with MCI during

our 9-year follow-up period. Being born immediately after versus

immediately before September 2, 1933, and thus being eligible

for HZ vaccination, decreased the occurrence of new diagnoses

of MCI over 9 years by 1.5 (95% conﬁdence interval [CI]: 0.5–2.9,

OPEN ACCESS

2 Cell 188, 1–16, December 11, 2025

Please cite this article in press as: Xie et al., The effect of shingles vaccination at different stages of the dementia disease course, Cell (2025),

https://doi.org/10.1016/j.cell.2025.11.007

Article

p = 0.006) percentage points (Figure 2). Scaled to the proportion

of individuals who took up HZ vaccination if they were eligible us-

ing our regression discontinuity approach, the effect of actually

receiving the HZ vaccination was a 3.1 (95% CI: 1.0–6.2, p =

0.007) percentage point reduction in new diagnoses of MCI

over 9 years. The effect across different follow-up periods is

shown in Figure S2. Both the effect of being eligible for HZ vacci-

nation and the effect of actually receiving the HZ vaccination

were robust across different choices of bandwidth, grace period,

and functional form (using local quadratic instead of local linear

regression), when requiring that a new MCI diagnosis not be fol-

lowed by a new dementia diagnosis within 0–3 months or within

0–6 months, when adjusting for the staggered rollout of the pro-

gram, when adjusting for indicators of health service utilization,

and when restricting the analysis cohort to frequent primary

care visitors (Figure S3).

A protective effect of HZ vaccination on deaths due to

dementia

Among our study cohort of individuals with a diagnosis of

dementia received prior to the start date of the HZ vaccination

program, 7,049 (49.1%) died due to dementia (i.e., had dementia

recorded as the underlying cause of death in their death certiﬁ-

cate) over the 9-year follow-up period. Being eligible for HZ

vaccination (i.e., being born shortly after versus shortly before

September 2, 1933) decreased the occurrence of deaths due

Table 1. Characteristics of each dataset used in this study

Dataset Description

Welsh Demographic Service Dataset

(WDSD)

This is a registry of all individuals registered with a primary care provider in Wales (over 98% of

adults residing in Wales are registered with a primary care provider

). The following variables

from this dataset were used in this study: date of birth in weeks, sex, individuals’ anonymized

address history (to deﬁne residence status in Wales), and the 2011 Welsh Index of Multiple

Deprivation (the government’s measure of relative deprivation for small areas in Wales

) for

each address history. Data were available until March 2023.

Welsh Longitudinal General Practice

dataset (WLGP)

This dataset contains comprehensive electronic health record data from primary care for

approximately 80% of primary care practices in Wales and 83% of the Welsh population. Our

study population was extracted from this dataset. All health events are encoded with Read

codes

and include diagnoses, clinical signs and observations, symptoms, medication

prescriptions, laboratory tests and results, procedures performed (including vaccinations), and

administrative items. This dataset formed the core of our analysis. All variables listed in Data S1

that include Read codes in their deﬁnition were at least partially ascertained using this dataset:

these variables include those needed to ascertain our study cohorts, primary and secondary

outcomes, HZ vaccination, diagnoses for our baseline balance checks and negative control

outcome analyses, uptake of preventive health services other than HZ vaccination, and

healthcare service utilization indicators. Data were available until January 2023.

Patient Episode Database for Wales

(PEDW)

This dataset contains electronic health record data for all inpatient and day case activity

undertaken in hospitals of NHS Wales as well as data on Welsh residents treated in hospitals

that are part of NHS England. Procedures are encoded using OPCS-4 codes

and diagnoses

using ICD-10 codes.

From this dataset, we used dates of admission (to identify the timing of a

speciﬁc diagnosis and ascertain our healthcare service utilization indicators) and diagnosis

codes (to identify a condition ﬁrst diagnosed in the hospital setting) in this study. The data

covered the period from April 1995 to March 2023.

Outpatient Database for Wales (OPDW)

This dataset contains attendance information for all hospital-based outpatient appointments.

We used dates of attendances from this dataset to ascertain our healthcare service utilization

indicators. Patients in the NHS generally have to obtain a referral from a primary care provider to

access outpatient specialist care

; thus, referrals to, and diagnoses made in, specialist care

are contained in the Welsh Longitudinal General Practice dataset. The data covered the period

from January 2004 to March 2023.

Welsh Cancer Intelligence and Surveillance

Unit (WCISU)

This is the national cancer registry for Wales, which records all cancer diagnoses given to Welsh

residents regardless of the setting in which they were diagnosed or treated. We used dates of

diagnoses (to identify the timing of a speciﬁc cancer diagnosis) and diagnosis codes (to identify

a speciﬁc cancer) from this dataset. The data covered the period from January 1994 to July

2022.

Annual District Death Extract (ADDE)

This is the national registry of all deaths of Welsh residents, including deaths of Welsh residents

that occurred outside of Wales. Cause-of-death data from death certiﬁcates used ICD-9 coding

until 2001 and ICD-10 coding thereafter. Dates for deaths were those on which the death was

registered, as opposed to when it occurred. The median delay between death occurrence and

registration in England and Wales in the years from 2001 to 2021 was 5 days.

We used date of

death (to identify the timing of death) as well as cause of death (both underlying and contributing

causes) in this study. More detailed information on mortality statistics in the United Kingdom is

available elsewhere.

The data covered the period from October 1973 to March 2023.

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Cell 188, 1–16, December 11, 2025 3

Please cite this article in press as: Xie et al., The effect of shingles vaccination at different stages of the dementia disease course, Cell (2025),

https://doi.org/10.1016/j.cell.2025.11.007

Article

Table 2. Sample characteristics at baseline of the two study cohorts in our analysis

Among patients without cognitive impairment at baseline

a,b,c,d,e

Variable

Full sample Sample in the MSE-optimal bandwidth

All Women Men All Women Men

n % n % n % n % n % n %

282,557 100.0 154,238 54.6 128,318 45.4 58,569 100.0 32,311 55.2 26,258 44.8

Quintile of

Welsh Index

of Multiple

Deprivation

1 (most deprived) 47,321 16.7 26,071 16.9 21,249 16.6 9,654 16.5 5,391 16.7 4,263 16.2

2 53,628 19.0 29,517 19.1 24,111 18.8 11,060 18.9 6,248 19.3 4,812 18.3

3 61,528 21.8 33,596 21.8 27,932 21.8 12,854 21.9 7,081 21.9 5,773 22.0

4 58,352 20.7 31,461 20.4 26,891 21.0 12,117 20.7 6,569 20.3 5,548 21.1

5 (least deprived) 61,728 21.8 33,593 21.8 28,135 21.9 12,884 22.0 7,022 21.7 5,862 22.3

Clinical

diagnoses

past shingles 34,280 12.1 20,461 13.3 13,819 10.8 7,611 13.0 4,592 14.2 3,019 11.5

ischemic heart disease 45,456 16.1 17,928 11.6 27,528 21.5 10,488 17.9 4,168 12.9 6,320 24.1

COPD 33,191 11.7 15,586 10.1 17,605 13.7 7,164 12.2 3,314 10.3 3,850 14.7

past stroke 20,938 7.4 10,028 6.5 10,910 8.5 4,879 8.3 2,362 7.3 2,517 9.6

past lower respiratory

tract infection

145,299 51.4 80,215 52.0 65,084 50.7 30,880 52.7 16,980 52.6 13,900 52.9

history of lung cancer 1,179 0.4 554 0.4 625 0.5 268 0.5 130 0.4 138 0.5

past fall(s) 52,620 18.6 35,998 23.3 16,622 13.0 11,897 20.3 8,161 25.3 3,736 14.2

history of colorectal cancer 5,662 2.0 2,445 1.6 3,217 2.5 1,295 2.2 557 1.7 738 2.8

history of lower back pain 126,210 44.7 72,251 46.8 53,959 42.1 26,471 45.2 15,379 47.6 11,092 42.2

history of breast cancer – – 6,450 4.2 – – – – 1,319 4.1 – –

history of pancreatic cancer 162 <0.1 81 <0.1 81 <0.1 28 <0.1 14 <0.1 14 <0.1

diabetes mellitus 55,354 19.6 26,289 17.0 29,065 22.7 12,185 20.8 5,903 18.3 6,282 23.9

Uptake of

preventive

health

measures

breast cancer screening – – 34,680 22.5 – – – – 5,952 18.4 – –

PPV-23 198,677 70.3 106,803 69.2 91,874 71.6 42,872 73.2 23,109 71.5 19,763 75.3

inﬂuenza vaccine 193,856 68.6 103,677 67.2 90,178 70.3 41,411 70.7 22,247 68.9 19,164 73.0

recent statin use 130,175 46.1 65,910 42.7 64,265 50.1 27,747 47.4 14,449 44.7 13,298 50.6

recent antihypertensive use 172,148 60.9 93,026 60.3 79,122 61.7 37,711 64.4 20,651 63.9 17,060 65.0

Among patients living with dementia at baseline

a,b,c,d,e

Variable

Full sample Sample in the MSE-optimal bandwidth

All Women Men All Women Men

n % n % n % n % n % n %

14,350 100.0 8,957 62.4 5,393 37.6 3,418 100.0 2,064 60.4 1,354 39.6

Quintile of

Welsh Index

of Multiple

Deprivation

1 (most deprived) 2,734 19.1 1,699 19.0 1,035 19.2 648 19.0 408 19.8 240 17.7

2 3,012 21.0 1,897 21.2 1,115 20.7 729 21.3 458 22.2 271 20.0

3 3,021 21.1 1,932 21.6 1,089 20.2 730 21.4 440 21.3 290 21.4

4 2,788 19.4 1,718 19.2 1,070 19.8 655 19.2 379 18.4 276 20.4

5 (least deprived) 2,795 19.5 1,711 19.1 1,084 20.1 656 19.2 379 18.4 277 20.5

Clinical

diagnoses

past shingles 1,761 12.3 1,176 13.1 585 10.8 400 11.7 254 12.3 146 10.8

ischemic heart disease 2,975 20.7 1,513 16.9 1,462 27.1 725 21.2 360 17.4 365 27.0

COPD 2,073 14.4 1,133 12.6 940 17.4 475 13.9 253 12.3 222 16.4

past stroke 2,654 18.5 1,461 16.3 1,193 22.1 640 18.7 325 15.7 315 23.3

past lower respiratory

tract infection

8,661 60.4 5,365 59.9 3,296 61.1 2,013 58.9 1,196 57.9 817 60.3

history of lung cancer 58 0.4 28 0.3 30 0.6 20 0.6 10 0.5 10 0.7

past fall(s) 6,652 46.4 4,608 51.4 2,044 37.9 1,476 43.2 983 47.6 493 36.4

history of colorectal cancer 285 2.0 138 1.5 147 2.7 60 1.8 25 1.2 35 2.6

history of lower back pain 6,530 45.5 4,161 46.5 2,369 43.9 1,573 46.0 996 48.3 577 42.6

history of breast cancer – – 298 3.3 – – – – 68 3.3 – –

history of pancreatic cancer <10 <0.1 <10 <0.1 <10 <0.1 <10 <0.1 <10 <0.1 <10 <0.1

diabetes mellitus 3,332 23.2 1,926 21.5 1,406 26.1 853 25.0 486 23.5 367 27.1

(Continued on next page)

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Please cite this article in press as: Xie et al., The effect of shingles vaccination at different stages of the dementia disease course, Cell (2025),

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Article

to dementia over 9 years by 8.5 (95% CI: 0.6–18.5, p = 0.036)

percentage points (Figure 2). The effect of actually receiving

the HZ vaccination was a 29.5 (95% CI: 0.6–62.9, p = 0.046) per-

centage point reduction in deaths due to dementia over 9 years.

Our difference-in-differences analysis (detailed in the STAR

Methods and Figure S11) yielded similar results as our regres-

sion discontinuity analysis (Figure 2). The effect across different

follow-up periods is shown in Figure S2. As for MCI as outcome,

the point estimates for the effect of being eligible for HZ vaccina-

tion and the effect of actually receiving the HZ vaccination were

robust across different choices of bandwidth, grace period, and

functional form (using local quadratic instead of local linear

regression) and when adjusting for the staggered rollout of the

program (Figure S3). In addition, the effect remained signiﬁcant

when adjusting for the baseline imbalance in ischemic heart dis-

eases diagnoses using a fully non-parametric regression discon-

tinuity method that can ﬂexibly control for such baseline imbal-

ances (Figure S3).

Evidence against the existence of confounding

Given the focus of our regression discontinuity approach on

changes in the outcome variable at the date-of-birth eligibility

threshold, a confounding variable would only bias our analysis

if it changed abruptly at the September 2, 1933, date-of-birth

threshold. Such bias could arise if another intervention used

the identical date-of-birth eligibility threshold (i.e., September

2, 1933) as the HZ vaccination program. As detailed in the

STAR Methods, we tested for this possibility in four ways.

First, the September 2 date-of-birth eligibility threshold only

had a signiﬁcant effect on our outcomes in the birth year

(1933) that was used by the HZ vaccination program but not

in any of the 3 birth years prior to and after 1933 (Figure S4).

This ﬁnding reduces the probability that an annual intervention

existed that also used September 2 as a date-of-birth eligibility

criterion.

Second, at the time of the start date of the HZ vaccination pro-

gram, we did not observe systematic differences across the

September 2, 1933, date-of-birth threshold in past preventive

health services uptake nor the prevalence of the ten leading

causes of DALYs and mortality among adults aged 70+ years in

Wales (Figure S1). Third, there were no signiﬁcant differences in

the incidence of new MCI diagnoses (in our study cohort for

analyzing the effect on MCI) and deaths due to dementia (in our

study cohort for analyzing the effect on deaths due to dementia)

across the September 2, 1933, date-of-birth threshold in the 9

years before the start of the HZ vaccination program (MCI: 0.0

[95% CI: − 0.5 to 0.6, p = 0.953] percentage points; deaths due

to dementia: − 5.2 [− 17.7 to 6.7, p = 0.375] percentage points).

Together, these tests reduce the likelihood that a competing inter-

vention (i.e., another intervention that used the identical date-of-

birth eligibility threshold as the HZ vaccination program) existed

that was implemented prior to the HZ vaccination program.

Fourth, other than for dementia, we did not observe any sig-

niﬁcant effects of the September 2, 1933, date-of-birth eligi-

bility threshold on diagnoses of each of the ten most common

causes of DALYs and mortality (in our study cohort for

analyzing the effect on MCI) and deaths due to the ten leading

causes of mortality (in our study cohort for analyzing the effect

on deaths due to dementia) among adults aged 70+ years in

Wales over our 9-year follow-up period (Figure 3). Neither did

we observe any effects on indicators of preventive health ser-

vices uptake during our follow-up period (Figure 3). These tests

provide evidence against the existence of an intervention that

used the identical date-of-birth eligibility threshold as the HZ

vaccination program and was not speciﬁcally designed to

only affect our primary outcomes.

Table 2. Continued

Among patients living with dementia at baseline

a,b,c,d,e

Variable

Full sample Sample in the MSE-optimal bandwidth

All Women Men All Women Men

n % n % n % n % n % n %

Uptake of

preventive

health

measures

breast cancer screening – – 1,327 14.8 – – – – 323 15.6 – –

PPV-23 10,478 73.0 6,330 70.7 4,148 76.9 2,512 73.5 1,473 71.4 1,039 76.7

inﬂuenza vaccine 9,586 66.8 5,840 65.2 3,746 69.5 2,263 66.2 1,331 64.5 932 68.8

recent statin use 6,596 46.0 3,863 43.1 2,733 50.7 1,650 48.3 938 45.4 712 52.6

recent antihypertensive use 7,535 52.5 4,608 51.4 2,927 54.3 1,801 52.7 1,058 51.3 743 54.9

Abbreviations are as follows: Sept, September; MSE, mean squared error; COPD, chronic obstructive pulmonary disease; PPV-23, pneumococcal

polysaccharide vaccine.

The baseline date was September 1, 2013 (the start date of the HZ vaccination program).

The length of the MSE-optimal bandwidth (used in our complier average causal effect analysis) was 95.1 weeks for patients without cognitive impair-

ment at baseline and 97.5 weeks for patients living with dementia at baseline.

Deciles of the Welsh Index of Multiple Deprivation (WIMD) were calculated based on the 2011 WIMD survey.

Breast cancer screening was deﬁned as the proportion of women with a record of referral to, attendance at, or a report from ‘‘breast cancer screening’’

or mammography at any time prior to September 1, 2013. ‘‘PPV-23’’ was deﬁned as receipt of the pneumococcal vaccine as an adult at any time prior

to September 1, 2013. ‘‘Inﬂuenza vaccine’’ was deﬁned as inﬂuenza vaccine receipt in the 12 months preceding September 1, 2013. Recent statin and

antihypertensive use was deﬁned as a new or repeat prescription of a statin or antihypertensive drug, respectively, in the 12 months preceding

September 1, 2013.

Diabetes mellitus referred to both diabetes mellitus type 1 and type 2.

OPEN ACCESS

Cell 188, 1–16, December 11, 2025 5

Please cite this article in press as: Xie et al., The effect of shingles vaccination at different stages of the dementia disease course, Cell (2025),

https://doi.org/10.1016/j.cell.2025.11.007

Article

The protective effects were larger among women than

men

The effect of HZ vaccination—both on reducing new diagnoses

of MCI and deaths due to dementia—was larger among women

than men (Figure 4). Among women, the effects of being eligible

for, and actually receiving, HZ vaccination on new diagnoses of

MCI were a reduction of 2.5 (95% CI: 1.1–4.5, p = 0.001) and 5.1

(95% CI: 2.6–9.8, p < 0.001) percentage points, respectively. The

corresponding estimates for the effects on deaths due to de-

mentia among women living with dementia at baseline were a

decrease of 13.9 (95% CI: 3.4–26.3, p = 0.011) and 52.3 (95%

CI: 9.2–97.9, p = 0.018) percentage points. For both MCI and

deaths due to dementia, the estimates among men were statis-

tically indistinguishable from zero. Formal interaction tests by

gender showed that the interaction was signiﬁcant for both

new MCI diagnoses (p = 0.029) and deaths due to dementia

(p = 0.039) (Table S1). The signiﬁcant effects among women

were robust across different choices of bandwidth, grace period,

and functional form (using local quadratic instead of local linear

regression), as well as when requiring that a new MCI diagnosis

not be followed by a new dementia diagnosis within 0–3 months

or within 0–6 months, adjusting for the staggered rollout of the

program, adjusting for indicators of health service utilization,

and restricting the analysis cohort to frequent primary care visi-

tors (Figure S5).

To examine whether the beneﬁts of HZ vaccination in reducing

deaths due to dementia also apply to those who already have

more advanced dementia, we additionally conducted a set of

subgroup analyses that divided those living with dementia at

the time of the start date of the HZ vaccination program into

those with more versus less severe dementia. To do so, we

used several indicators—as measured prior to September 1,

2013—that we hypothesized likely reﬂect dementia severity: (1)

risk of all-cause mortality, as predicted from each condition

that is part of the Charlson comorbidity index

; (2) the total num-

ber of days spent as an inpatient in hospital (as part of admis-

sions for which dementia was recorded as a primary or second-

ary reason); (3) the number of hospital admissions (for which

dementia was recorded as a primary or secondary reason); (4)

the number of times that a diagnosis of dementia was recorded

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

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p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 45.9

95% CI: [44.7,47.8]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 43.6

95% CI: [41.8,46.1]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Coef.: 50.5

95% CI: [48.8,52.9]

p<0.001

Full population Women Men

−156 −104 −52 0 52 104 156

−156 −104 −52 0 52 104 156 −156 −104 −52 0 52 104 156

Week of birth (relative to Sept 2 1933)

Ever had the HZ vaccine (in %)

0.00 0.25 0.50 0.75 1.00

Weight

Among patients without cognitive impairment at baseline

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 28.7

95% CI: [23.9,35.5]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 26.5

95% CI: [20.8,34.4]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Coef.: 32.0

95% CI: [25.1,41.0]

p<0.001

Full population Women Men

−156 −104 −52 0 52 104 156 −156 −104 −52 0 52 104 156 −156 −104 −52 0 52 104 156

Week of birth (relative to Sept 2 1933)

Ever had the HZ vaccine (in %)

0.00 0.25 0.50 0.75 1.00

Wei ght

Among patients living with dementia at baseline

Figure 1. The abrupt change in the probability of receiving the HZ vaccination at the September 2, 1933, date-of-birth eligibility threshold

‘‘Baseline’’ refers to the start date of the HZ vaccination program (i.e., September 1, 2013). Linear regression lines were drawn in the mean squared error-optimal

bandwidth only. Gray dots show the mean value for each 10-week increment in week of birth. The gray shading of the dots is in proportion to the weight that

observations from this 10-week increment received in the analysis.

Abbreviations are as follows: HZ, herpes zoster; Coef., coefﬁcient; CI, conﬁdence interval; Sept, September.

See also Figures S8 and S9.

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Article

the date-of-birth eligibility threshold (September 2, 1933) for HZ

vaccination. On average, individuals in Wales born in one week

versus merely a week later would not be expected to differ in their

health characteristics and behaviors. In the case of the

September 2, 1933, threshold, however, there was a large differ-

ence in the probability of ever receiving the HZ vaccine between

these groups, who differed in age by merely a week. The eligibility

rules of the HZ vaccination program in Wales thus created two

comparison groups—just on either side of the September 2,

1933, threshold—who were (after ﬂexibly controlling for age)

likely similar to each other except for their probability of receiving

the intervention of interest (HZ vaccination). As a result, the

ﬁndings from our analysis are more likely to reﬂect a causal rela-

tionship than are those from the associational epidemiological

evidence (Figures S10 and S11).

26–35,67,68

The critical advantage of our quasi-randomization approach

is that a confounding variable can only bias our analysis if it

changes abruptly at the September 2, 1933, date-of-birth

threshold.

41,42

Such an abrupt change in a confounding variable

at the September 2, 1933, date-of-birth threshold might exist if

there were another intervention that used the identical date-of-

birth threshold as its eligibility criterion as did the HZ vaccination

program. We conducted a series of tests to investigate whether

the existence of such an intervention is likely. Speciﬁcally, individ-

uals born just on either side of the September 2, 1933, date-of-

birth threshold were well-balanced at baseline in their past pre-

ventive health services uptake, prevalence of common causes

of morbidity and mortality, and past incidence of MCI and deaths

due to dementia. Similarly, there was no effect of the September

2, 1933, date-of-birth threshold on common health outcomes

(other than dementia) during our 9-year follow-up period, nor on

preventive health services uptake indicators (other than HZ

vaccination). Lastly, the September 2 date-of-birth threshold

only had an effect on MCI and deaths due to dementia in the birth

year (1933) that was used by the HZ vaccination program as its

eligibility criterion. Thus, none of our tests suggested the exis-

tence of another intervention that also used the date of birth of

September 2, 1933, as its eligibility criterion. It is in our view

also unlikely that HZ vaccination led to increased uptake of other

preventive health services (e.g., the uptake of other vaccines at

the same visit) because we did not observe any effect of HZ

vaccination eligibility on available indicators of preventive health

services among older adults in our data.

We believe that our repeated ﬁndings from natural experiment

studies of a beneﬁcial effect of HZ vaccination on the dementia

disease process call for further investments in this area of

research, not only to conﬁrm the effects but also to elucidate

the mechanisms. Although only suggestive, our exploratory ana-

lyses showing larger relative reductions for mixed dementia than

for Alzheimer’s disease and vascular dementia point to a mecha-

nism that is at play in both Alzheimer’s disease and vascular de-

mentia—and potentially other dementia types as well. Several

such potential mechanisms have been outlined recently,

and

these suggest that HZ vaccination may protect neuroimmune

health in older age more broadly as well as counteracting immu-

nosenescence. There is also evidence that reactivations of the

varicella zoster virus can lead to long-lasting cognitive impairment

through vasculopathy,

69,70

amyloid deposition and aggregation of

tau proteins,

and neuroinﬂammation,

13–16

as well as a pattern of

cerebrovascular disease that is similar to that seen in Alzheimer’s

disease, such as small- to large-vessel disease, ischemia, infarc-

tion, and hemorrhage.

11–16

In addition, reactivations of the vari-

cella zoster virus may lead to reactivations of the herpes simplex

virus in the brain.

71,72

This ﬁnding, in turn, would link HZ vaccina-

tion to the more extensive literature on the herpes simplex virus as

a causative factor in the development of dementia.

3,73

A recent

analysis of electronic health record data from the United States

found that indicators of a higher burden of reactivations of the vari-

cella zoster virus were associated with an increased risk of de-

mentia.

Speciﬁcally, the authors reported a consistent pattern

of a higher burden of varicella zoster virus reactivations (as as-

sessed by comparing dementia risk in those with multiple versus

single shingles episodes) being associated with a higher dementia

risk, whereas a lower burden (as assessed by comparing demen-

tia risk in those who received an HZ vaccine versus those who

received a pneumococcal vaccine, two doses versus one dose

of the recombinant subunit HZ vaccine, and the live-attenuated

versus the recombinant subunit HZ vaccine) was associated

with a lower dementia risk. The analysis also found that the pro-

tective association of HZ vaccination with dementia risk was

largest among women and older patients—groups who are at a

higher risk of shingles.

59,60,74

Importantly, however, although ﬁnd-

ings were consistent across analyses, each analysis is subject to

the risk of residual confounding and thus correlational in nature

only. It may also, therefore, be the case that a pathogen-indepen-

dent immunomodulatory mechanism is involved, as possibly sug-

gested by our repeated ﬁnding of a strong effect heterogeneity by

gender.

Some of these potential immune mechanisms have

recently been described elsewhere.

17,18

Limitations of the study

This study has several important limitations. First, our ﬁndings

pertain to those age groups born near to the September 2,

1933, date-of-birth threshold (primarily those aged 79–80 years).

It is possible that the protective effects observed in this study do

not exist, or are of a different magnitude, in younger age groups,

given that the neuropathology and pathophysiology of dementia

varies strongly by age.

75–79

In addition, the immune system ap-

pears to change in a multitude of characteristics during the last

decades of life,

which could inﬂuence any role that the varicella

zoster virus or a virus-independent immunomodulatory effect

induced by the live-attenuated HZ vaccine may have in the de-

mentia disease process. Another reason that effects of the HZ

vaccine on dementia-related outcomes may differ by age is

that the efﬁcacy of the live-attenuated HZ vaccine for preventing

HZ is lower in older than in younger age groups.

58,81

Second,

given its implementation using local linear regression, regression

discontinuity is only able to reliably estimate absolute as

opposed to relative effects.

41,82

Third, we were limited to infor-

mation contained in electronic health record and death certiﬁ-

cate data to deﬁne our study cohorts and outcomes. It is likely

that there is considerable underascertainment in our data for

cognitive impairment (to deﬁne the cognitively unimpaired study

cohort for our ﬁrst aim), dementia (to deﬁne the study cohort of

individuals living with dementia for our second aim), MCI, and

deaths due to dementia. Crucially, however, the degree of

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Article

underascertainment (as well as any delay in making these diag-

noses or in changes in data quality over time) is unlikely to differ

between individuals born just before versus just after September

2, 1933. As such, other than potential underestimation of the

true beneﬁts of HZ vaccination on an absolute scale, underas-

certainment of these variables was unlikely to bias our analysis.

Fourth, we were also limited to the information available in

electronic health record data to deﬁne the two stages of the dis-

ease course of dementia analyzed in this study. We, for instance,

had no information on β-amyloid or tau pathology or results from

detailed neuropsychological assessments. Fifth, the COVID-19

pandemic started within our follow-up period and may have de-

layed new diagnoses of MCI as well as changed mortality rates

among individuals living with dementia. However, as for our third

limitation, the pandemic affected individuals born just on either

side of the September 2, 1933, date-of-birth threshold equally.

Sixth, some diagnoses of MCI in our data may have mistakenly

been made for individuals who already had mild-to-moderate

dementia. We believe that this is unlikely to be a major limitation

of our analysis, given that our effect estimates remained signiﬁ-

cant when requiring that a new diagnosis of MCI not be followed

by a new diagnosis of dementia within 3 months or within 6

months. Seventh, we observed an imbalance in past ischemic

heart disease diagnoses across the September 2, 1933,

threshold among the study cohort for our second aim. We, how-

ever, show in Tables S1 and S2 that our results were robust to

any adjustment for this imbalance. In our view, this imbalance

was likely a chance ﬁnding, given that it was the only difference

with a p value less than 0.05 in 36 (18 among each of our two

study cohorts) baseline balance tests that we conducted. Lastly,

our results pertain to the live-attenuated HZ vaccine (Zostavax,

Merck) only, because the newer recombinant HZ vaccine (Shing-

rix, GSK) was introduced into the UK’s National Health Service

after our follow-up period ended.

Conclusions

In conclusion, this study suggests that HZ vaccination slows or

prevents disease progression across the entire disease course

(as far as it can be feasibly ascertained from electronic health re-

cord data) of dementia. By taking advantage of the fact that the

UK’s National Health Service assigned individuals who differed

in their age by just a few weeks to being eligible or ineligible for

HZ vaccination based on their date of birth, we were able to

generate evidence that is more likely to be causal than those

from more standard epidemiological analyses. Our ﬁnding that

HZ vaccination had a beneﬁcial effect on two different demen-

tia-related outcomes in two different patient samples—and at

two opposing ends of the disease course of dementia—thus pro-

vides promising evidence that HZ vaccination may prevent or

slow the dementia disease process in a substantial proportion

of individuals.

RESOURCE AVAILABILITY

Lead contact

Requests for further information and resources should be directed to, and will

be fulﬁlled by, the lead contact, Pascal Geldsetzer (pgeldsetzer@stanford.

edu).

Materials availability

This study did not generate new unique reagents.

Data and code availability

•

The data that support the ﬁndings of this study are available from the

SAIL databank.

Researchers must request access to the data directly

from SAIL. The authors have no permission to share the data.

•

All statistical analysis code (in R) has been deposited in a publicly

accessible OSF repository at https://osf.io/nwz8h/?view_only=2311

79cb8d7045f3be22b0979634d9c3. All Read and ICD codes to deﬁne

variables are available in Data S1.

•

Any additional information required to reanalyze the data reported in this

paper is available from the lead contact upon request.

ACKNOWLEDGMENTS

This study makes use of anonymized data held in the SAIL databank. The au-

thors are grateful for the continuous advice and support from the SAIL data-

bank analytical services team throughout all stages of the project. We would

also like to acknowledge all the data providers who made anonymized data

available for our research. The responsibility for the interpretation of the data

supplied by SAIL is the authors’ alone. SAIL bears no responsibility for the

further analysis or interpretation of their data over and above that published

by SAIL.

This study was funded by grants to P.G. by The Phil & Penny Knight Initiative

for Brain Resilience at the Wu Tsai Neurosciences Institute, Stanford University

(KPI-003); the National Institute on Aging (R01AG084535); National Institute of

Allergy and Infectious Diseases (DP2AI171011); and Chan Zuckerberg

Biohub-San Francisco. The funders had no role in the design and conduct of

the study; collection, management, analysis, and interpretation of the data;

preparation, review, or approval of the manuscript; or the decision to submit

the manuscript for publication.

AUTHOR CONTRIBUTIONS

M.X. and M.E. devised the methodology, analyzed and processed the data,

created data visualizations, interpreted the results, and reviewed and edited

the original draft. C.B. co-devised the methodology, interpreted the results,

and reviewed and edited the original draft. H.A. interpreted the results and

reviewed and edited the original draft. P.G. conceived the overall project,

acquired funding, conceived the study, devised the methodology, was respon-

sible for administration and supervision, interpreted the results, wrote the orig-

inal draft, and reviewed and edited the original draft.

DECLARATION OF INTERESTS

The authors declare no competing interests.

STAR★METHODS

Detailed methods are provided in the online version of this paper and include

the following:

•

KEY RESOURCES TABLE

•

EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS

○

Human participants

•

METHOD DETAILS

○

Study cohorts and follow-up period

○

Exposure and outcome deﬁnition

○

Ethics

•

QUANTIFICATION AND STATISTICAL ANALYSIS

○

Regression discontinuity analysis

○

Testing for confounding

○

Testing for ascertainment bias

○

Evidence triangulation

○

Effect heterogeneity analyses

○

Regression equations

OPEN ACCESS

12 Cell 188, 1–16, December 11, 2025

Please cite this article in press as: Xie et al., The effect of shingles vaccination at different stages of the dementia disease course, Cell (2025),

https://doi.org/10.1016/j.cell.2025.11.007

Article

SUPPLEMENTAL INFORMATION

Supplemental information can be found online at https://doi.org/10.1016/j.cell.

2025.11.007.

Received: April 13, 2025

Revised: September 16, 2025

Accepted: November 5, 2025

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STAR★METHODS

KEY RESOURCES TABLE

EXPERIMENTAL MODEL AND STUDY PARTICIPANT DETAILS

Human participants

Allocation to exposure groups based on the herpes zoster vaccine rollout in Wales

Starting on September 1 2013, the National Health Service ([NHS], the United Kingdom’s single-payer single-provider healthcare sys-

tem

) in Wales made the live-attenuated HZ vaccine (Zostavax, Merck) available to a catch-up cohort of individuals using a stag-

gered rollout system based on speciﬁc date-of-birth eligibility thresholds.

Individuals who did not yet have their 80

birthday on

the start date of the program (i.e., born on or after September 2 1933) were eligible for one year. By contrast, those who had their

birthday prior to the program start date (i.e., born before September 2 1933) never became eligible.

Speciﬁcally, individuals were categorized into three cohorts based on their date of birth: i) a routine cohort consisting of individuals

born on or after September 2 1942 who became eligible when they were 70 years old as of September 1 of a given year of the HZ

vaccination program; ii) a catch-up cohort consisting of individuals born between September 2 1933 and September 1 1942 who

became eligible when they were 79 years (or 78 years, depending on the year of the program) as of September 1 of a given year

of the HZ vaccination program and remained eligible until they were 80 years old (again, as of September 1 of a given year of the

HZ vaccination program); and iii) individuals born on or before September 1 1933 (i.e., aged 80 years and older as of September

1 2013) who never became eligible.

Our analysis was restricted to adults born between September 1 1925 (88 years old on the start date of the HZ vaccination pro-

gram) and September 1 1942 (71 years old on the start date of the HZ vaccination program). Those born between September 1 1925

and September 1 1933 were never eligible for HZ vaccination, whereas those born between September 2 1933 and September 1

1942 became eligible as part of the catch-up cohort mentioned above. Speciﬁcally, the vaccine was offered to those born between:

September 2 1933 and September 1 1934 in the ﬁrst year of the program (September 1 2013 to August 31 2014); September 2 1934

and September 1 1936 in the second year (September 1 2014 to August 31 2015); September 2 1936 and September 1 1937 in the

third year (September 1 2015 to August 31 2016); and September 2 1937 and September 1 1938 in the fourth year (September 1 2016

to August 31 2017). As of April 1 2017, individuals became eligible for the vaccine on their 78

birthday and remained eligible until their

birthday.

Data source and sample size

This study used the Secure Anonymised Information Linkage (SAIL) Databank.

38,85

This databank provides detailed electronic health

record data from primary care in the NHS through the Welsh Longitudinal General Practice dataset,

which contains data on diag-

noses, clinical signs and observations, symptoms, laboratory tests and results, procedures performed (including vaccinations), pre-

scribed medications, and administrative items.

Using individuals’ unique NHS number, SAIL links this primary care dataset to

a series of databases. For our study, these databases consisted of the Welsh Demographic Service Dataset,

the Patient

Episode Database for Wales (containing hospital-based inpatient care data),

the Outpatient Database for Wales (containing

REAGENT or RESOURCE SOURCE IDENTIFIER

Deposited data

Welsh Demographic Service Dataset

(WDSD)

SAIL databank ID: 1306

Welsh Longitudinal General Practice

dataset (WLGP)

SAIL databank ID: 1306

Patient Episode Database for Wales

(PEDW)

SAIL databank ID: 1306

Outpatient Database for Wales (OPDW) SAIL databank ID: 1306

Annual District Death Extract (ADDE) SAIL databank ID: 1306

Welsh Cancer Intelligence and Surveillance

Unit (WCISU)

SAIL databank ID: 1306

Software and algorithms

R 4.3.3 R Core Team http://r-project.org/

Omnissa Horizon Client 2503 Omnissa https://www.omnissa.com/products/

horizon-8/

DB2 11.1 IBM https://www.ibm.com/products/db2

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specialist-based ambulatory care data),

the Welsh Cancer Intelligence and Surveillance Unit (containing data on care for cancer),

and the Annual District Death Extract (containing cause-of-death data).

Our data included individuals’ date of birth in weeks (with

weeks starting on a Monday). A description of each dataset, including the years covered by the data, is provided in Table 2.

We restricted our dataset to all individuals born between September 1 1925 and September 1 1942 who were ever registered with a

primary care provider in the Welsh Longitudinal General Practice Dataset and who were alive and residing in Wales as of the start date

of the HZ vaccination program (September 1 2013). The resulting sample size was 304,940 individuals, of whom 167,461 were re-

corded as female, 137,478 as male, and 1 as ‘‘unspeciﬁed’’ gender.

METHOD DETAILS

Study cohorts and follow-up period

Given that each patient in our dataset had a unique anonymized NHS number, we were able to follow patients over time even if they

changed primary care provider. We deﬁned one study cohort for each of our two aims. For determining the effect of HZ vaccination on

the incidence of MCI, we excluded patients whose electronic health record data suggested any cognitive impairment at any time prior

to the start date of the HZ vaccination program. To do so, we used the code list for cognitive impairment published by Moran et al.

(also shown in Data S1),

which consists of detailed Read codes for any symptoms, signs, and diagnoses relating to cognitive

impairment, such as disturbances of memory, orientation, concentration, or reasoning, as well as formal diagnoses of MCI and de-

mentia. For determining the effect of HZ vaccination on the occurrence of deaths due to dementia, we restricted our analysis cohort

to those patients with a diagnosis of dementia made at any time prior to the start date of the HZ vaccination program. This cohort is

henceforth referred to as patients living with dementia at baseline. The Read and ICD codes used to deﬁne dementia (as well as all

other diagnoses used in this study) are provided in Data S1.

The follow-up period for all primary analyses was nine years, starting on September 1 2013 (the start date of the HZ vaccination

program) and ending on August 31 2022. In secondary analyses, we show all results when using follow-up periods from one to nine

years in one-year increments.

Exposure and outcome deﬁnition

The exposure was eligibility for HZ vaccination based on one’s date of birth. As shown in Figure S10, most eligible patients (especially

in the ﬁrst two eligibility cohorts of the phased rollout, which are the focus of our analysis) in each of our two study populations took up

HZ vaccination during their ﬁrst year of eligibility.

For determining the effect of HZ vaccination on MCI, our primary outcome was MCI as deﬁned by a record of a Read code (see

Data S1) for MCI in our electronic health record data. As robustness check, we required that the ﬁrst diagnosis of MCI not be followed

by a new dementia diagnosis within three and within six months to examine the sensitivity of our ﬁndings to the possibility of a patient

with mild-to-moderate dementia being falsely classiﬁed as having MCI. For determining the effect of HZ vaccination on deaths due to

dementia, our primary outcome was deﬁned as dementia being named as the underlying (i.e., primary) cause of death in the patient’s

death certiﬁcate (see Data S1 for ICD-10 codes used). We deﬁned dementia as dementia of any type because of our reduced sta-

tistical power when studying less common outcomes, as well as the neuropathological overlap between dementia types and difﬁculty

in distinguishing dementia types clinically.

98–100

Dates of deaths were for the date of death registration as opposed to occurrence,

whereby the median delay between death occurrence and registration in Wales in the years from 2001 to 2021 was ﬁve days.

We used all-cause mortality among patients living with dementia at baseline as a secondary outcome. The rationale for analyzing

this secondary outcome was that if HZ vaccination reduced deaths due to dementia, it will be important to ascertain whether this

effect led to an increase in remaining life expectancy (in which case we would also observe a reduction in all-cause mortality) or

merely to the replacement of dementia as the underlying cause of death on the death certiﬁcate with the mentioning of another cause

(in which case we would observe no effect on all-cause mortality). The Read and ICD codes used to deﬁne all our outcomes, including

those used as baseline balance checks and in negative control outcome analyses, as well as HZ vaccination are provided in Data S1.

Exploratory outcomes in our analyses were diagnoses of dementia by type. In these analyses, we concentrated on women

because our heterogeneous treatment effect analyses indicated that the observed protective effects of HZ vaccination were predom-

inantly driven by this group. We restricted our comparisons to the three most common dementia types in our dataset (Alzheimer’s

disease, vascular dementia, and mixed dementia) to avoid overly small sample sizes. We only considered diagnoses made in hos-

pital-based rather than primary care. Hospital-based assessments are more likely to involve comprehensive evaluations, including

brain imaging,

thereby likely increasing diagnostic accuracy. Because dementia types differ substantially in incidence, we

compared relative rather than absolute effects. Estimating relative effects within a regression discontinuity framework, however, pre-

sents methodological constraints, as there is no established approach for calculating conﬁdence intervals or p-values for these es-

timates.

We therefore report point estimates only. We examined the effect of both HZ vaccination eligibility and receipt on dementia

diagnoses by type in two cohorts: i) women without a dementia diagnosis at baseline (i.e., the same cohort as used in Eyting et al.

);

and ii) women without any record of cognitive impairment at baseline (i.e., the same cohort used for our MCI outcome analysis). We

also conducted an analysis focusing on dementia diagnoses that occurred after an MCI diagnosis during the follow-up period. For

this analysis, we considered dementia diagnoses made in any care setting to maintain more adequate sample sizes.

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Ethics

Approval was granted by the Information Governance Review Panel (IGRP, application number: 1306), which oversees and approves

applications to use the SAIL databank. This research was also approved by the Stanford University Institutional Review Board on

June 9 2023 and considered minimal risk (protocol number: 70277).

QUANTIFICATION AND STATISTICAL ANALYSIS

The two authors who analyzed the data (M.E. and M.X.) conducted all parts of the analysis independently, compared their results,

and, in the case of any discrepancies, agreed on the preferred coding approach through discussion.

Regression discontinuity analysis

Patients born immediately before versus immediately after September 2 1933 would be expected to be exchangeable (i.e., similar in

observable and unobservable characteristics) with each other except for their probability of receiving HZ vaccination (as a result of

their eligibility status for HZ vaccination). Our analysis approach was guided by this expectation.

Regression discontinuity (RD) is a well-established method for causal effect estimation for such threshold-based exposure assign-

ments.

This technique estimates the outcome probability for individuals just on either side of the September 2 1993 date-of-birth

eligibility threshold. As per recommended practice for RD,

41,42,82

we used a mean squared error (MSE)-optimal bandwidth with

robust bias-corrected standard errors,

101

and assigned a higher weight to observations closer to either side of the September 2

1933 date-of-birth eligibility threshold using triangular kernel weights. The MSE-optimal bandwidth was calculated separately for

each combination of study cohort and outcome deﬁnition. We used local linear regression because it is the recommended and

most reliable approach for RD analyses even when the relationship between date of birth and the outcome in the entire dataset is

exponential.

102

However, in robustness checks, we also analyzed our data using local quadratic instead of linear regression. Higher

polynomial regressions are not recommended for RD.

102

In addition, we veriﬁed that our results were not dependent on the choice of

i) bandwidth (by using bandwidth choices of 0.50, 0.75, 1.25, 1.50, 1.75, and 2.00 times the MSE-optimal bandwidth), and ii) grace

period (i.e., the time since the index date after which follow-up time is considered to begin to allow for the time needed for a full im-

mune response to develop after vaccine administration). In an additional robustness check, we adjusted the follow-up period to ac-

count for the staggered rollout of the HZ vaccination program. Thus, instead of starting the follow-up period for all individuals on

September 1 2013, we started the follow-up period for each individual on the date on which they ﬁrst became eligible for HZ vacci-

nation. We added cohort ﬁxed effects in these analyses to control for the one- to two-year (depending on the program year) differ-

ences between eligibility cohorts in the start of their follow-up period.

For all outcomes, we estimated both the effect of being eligible for HZ vaccination based on one’s date of birth (the intent-to-treat

[ITT] effect), as well as the effect of actually receiving HZ vaccination (the complier average causal effect [CACE]). To estimate the

CACE, we followed standard practice for RD by implementing a so-called fuzzy RD.

While still comparing individuals just on either

side of the date-of-birth eligibility threshold, fuzzy RD corrects the effect estimates for the fact that a proportion of eligible individuals

did not receive the vaccine and a small proportion of ineligible individuals did receive the vaccine. Fuzzy RD is implemented by using

an instrumental variable approach.

In our analysis, the instrumental variable was a binary indicator for whether or not an individual

was eligible for HZ vaccination (i.e., born on or after versus born before September 2 1933). This analysis, therefore, adjusted the

effect size of being eligible for HZ vaccination for the magnitude of the abrupt change in the probability of receiving HZ vaccination

at the September 2 1933 threshold. Importantly, fuzzy RD does not compare eligible vaccine recipients with eligible vaccine non-re-

cipients because these groups likely have different health characteristics and behaviors (and, thus, confounding is likely).

Given its implementation using local linear regression, RD yields absolute as opposed to relative effect estimates. All regression

equations used in our analyses are shown in the last section of the STAR Methods.

Testing for confounding

The key advantage of our quasi-randomization approach is that a confounding variable can only bias our analysis if the variable

changes abruptly at the September 2 1933 date-of-birth threshold.

41,42

Thus, confounding bias is unlikely unless another intervention

existed that used the identical date-of-birth eligibility threshold (i.e., September 2 1933) as the HZ vaccination program. We inves-

tigated whether such a competing intervention was likely to exist in four ways.

First, if another intervention that used the identical date-of-birth eligibility threshold had been implemented prior to the HZ vacci-

nation program, then we may expect to observe differences in patients’ health characteristics or past uptake of preventive health

services at the time of the start date of the HZ vaccination program. We, therefore, tested for differences (using the same RD

approach as we used for our primary outcomes) across the September 2 1933 date-of-birth threshold in the prevalence of i) diag-

noses made at any time prior to September 1 2013 for each of the ten most common causes of disability-adjusted life years

(DALYs) and mortality among the age group 70+ years in Wales,

and ii) indicators of past preventive health services uptake. The

indicators of past preventive health services uptake available in our data were inﬂuenza vaccine receipt in the 12 months preceding

program start, receipt of the pneumococcal vaccine as an adult, current statin use (deﬁned as a new or repeat prescription of a statin

in the 12 months preceding program start), current use of an antihypertensive medication (deﬁned as a new or repeat prescription of

an antihypertensive drug in the 12 months preceding program start), and breast cancer screening participation (deﬁned as the

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proportion of women with a record of referral to, attendance at, or a report from ‘‘breast cancer screening’’ or mammography at any

time prior to the start date of the HZ vaccination program). The codes used to deﬁne each of these variables is provided in Data S1.

Second, if a dementia-speciﬁc intervention that used the identical date-of-birth eligibility threshold had been implemented before

the HZ vaccination program, then we may expect to observe differences in the incidence of our outcomes across the September 2

1933 threshold prior to the start date of the HZ vaccination program. We, thus, conducted the identical analysis as for our primary

outcomes except for starting the follow-up period nine years prior to the start date (September 1 2013) of the HZ vaccination

program.

Third, if an annual intervention used September 2 as a date-of-birth eligibility criterion, then we may expect to observe signiﬁcant

differences in our outcomes at the September 2 date-of-birth threshold for birth years other than 1933. We, thus, implemented the

same analyses as we did for the September 2 1933 threshold for the September 2 threshold of each of the three years of birth pre-

ceding and succeeding 1933 (i.e., date-of-birth thresholds of September 2 1930, September 2 1931, September 2 1932, September 2

1934, September 2 1935, and September 2 1936). To ensure that our analyses at these additional date-of-birth thresholds compared

individuals of the same age range as in our primary analyses, we shifted the start and end date of the follow-up period to the same

extent as the date-of-birth threshold. To maintain the same follow-up period in all comparisons, we, therefore, had to use a follow-up

period of six as opposed to nine years. As an example, when comparing individuals across the September 2 1930 threshold, we

started the follow-up period on September 1 2010 and ended the follow-up period on August 31 2016.

Fourth, unless another intervention that used the identical date-of-birth eligibility threshold was speciﬁcally designed to affect MCI

and dementia only, we may expect to see an effect of such an intervention on health outcomes other than MCI, dementia, and deaths

due to dementia. We, thus, conducted the same analysis as for our primary outcomes but for diagnoses of, and deaths due to, each of

the ten leading causes of DALYs and mortality in Wales for the age group 70+ years,

as well as indicators of preventive health ser-

vices uptake available in our data. The indicators of preventive health services uptake were breast cancer screening among women

(deﬁned as a record of referral to, attendance at, or a report from ‘‘breast cancer screening’’ or mammography at any time after the

start date of the HZ vaccination program), and, for the 12 months after the start of the HZ vaccination program, uptake of inﬂuenza

vaccination as well as any prescription of a statin or antihypertensive medication. Among patients without a record of cognitive

impairment prior to the start date of the HZ vaccination program, a new diagnosis of a given condition was deﬁned as the diagnosis

being recorded for the ﬁrst time in our electronic health record data or as an underlying or contributing cause on the death certiﬁcate.

Among patients with a diagnosis of dementia made prior to the start date of the HZ vaccination program, a death was considered to

be caused by a given condition if it was recorded as the underlying cause of death on the death certiﬁcate.

Testing for ascertainment bias

If healthcare seeking for episodes of shingles constituted an important opportunity for the health system to identify previously undi-

agnosed MCI, then our analysis for the effect of HZ vaccination on MCI could suffer from ascertainment bias. We conducted three

robustness checks to investigate whether this potential ascertainment bias was likely to represent an important source of bias in this

study. First, if shingles episodes were an important opportunity for the health system to detect previously undiagnosed chronic con-

ditions, then we may expect to observe an effect of HZ vaccination not only on MCI but also on other common chronic conditions. As

described in the preceding section, we, therefore, implemented the same RD analysis as for MCI but for each of the ten leading

causes of DALYs and mortality in Wales in 2019 for the age group 70+ years as outcomes.

Second, if healthcare utilization for shin-

gles had an important bearing on the health system’s ability to diagnose MCI, then we may expect that controlling for indicators of

healthcare utilization during the follow-up period would attenuate our effect estimates. We, therefore, adjusted our regressions for the

number of primary care visits, outpatient visits, hospital admissions, and inﬂuenza vaccinations received during our nine-year follow-

up period. Third, patients who frequently visit their primary care provider may be more likely to be (whether formally or informally)

screened for MCI. An analysis in this cohort of patients should, therefore, be less susceptible to ascertainment bias. We, thus,

also implemented our analysis when restricting our study population to the sample of those 135,712 (48.0% of the analysis cohort

for our primary analyses for MCI) patients who had made at least one visit to their primary care provider during each of the ﬁve years

preceding the start of the HZ vaccination program.

Evidence triangulation

We used a second quasi-experimental approach, namely a difference-in-differences (DID) analysis, to further investigate the robust-

ness of our RD ﬁndings. After restricting our sample to patients born between March 1 1926 and February 28 1934, we implemented

our DID approach by dividing our sample into yearly birth cohorts centered around September 1. We then divided each yearly birth

cohort into a pre-September birth ‘‘season’’ and a post-September birth season. The pre-September birth season was, thus, deﬁned

as the six-months period of March 1 to August 31 and the post-September birth season as the six-months period from September 1

to February 28 of the succeeding year. Our DID model tested whether the difference in outcomes across birth seasons was different

for the 1933/1934 birth cohort compared to other yearly birth cohorts. The rationale for our DID was that HZ vaccination eligibility only

differed between the two birth seasons in the 1933/1934-cohort but not in other yearly birth cohorts. The DID approach naturally ad-

justs for any potential systematic differences between pre-September and post-September birth seasons. The regression equations

for this DID approach are detailed in the last section of the STAR Methods.

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Importantly, our DID did not rely on the continuity assumption (i.e., the assumption that potential confounding variables do not

abruptly change at exactly the September 2 1933 date-of-birth eligibility threshold) made by RD. Instead, our DID relied on the

assumption that had the HZ vaccination program not existed, then the difference in our outcomes between the pre- and post-

September birth seasons would have been the same in the 1933/1934-cohort as in other yearly cohorts. A strength of our approach

is that we were able to investigate whether this assumption was likely to be met by testing whether there were signiﬁcant between-

birth-season differences in our outcomes in cohorts other than the 1933/1934-cohort. We did identify such signiﬁcant differences for

MCI among patients without a record of cognitive impairment at baseline, but not for deaths due to dementia among patients living

with dementia at baseline. Details are provided in Figure S11. We, therefore, used the DID approach only when analyzing the effect of

HZ vaccination on deaths due to dementia.

Effect heterogeneity analyses

In our previous analysis for the effect of HZ vaccination on new diagnoses of dementia,

we found a stronger effect among women

than men. We, therefore, tested for an effect heterogeneity by gender in both of our aims. To do so, in addition to analyzing the effect

among women and men separately, we implemented an interaction model that estimated the difference in effects by gender (the

regression equations for this analysis are provided in the last section of the STAR Methods).

We additionally conducted a set of subgroup analyses that aimed to provide suggestive evidence on whether the protective effect

for deaths due to dementia also exists among those already living with more advanced dementia at the time of the start date of the HZ

vaccination program. We used ﬁve measures, all of which were measured during the time period prior to September 1 2013, that we

hypothesized are likely correlated with the degree of dementia severity: i) the total number of inpatient days spent in hospital as part of

admissions for which dementia was recorded as the principal or secondary reason; ii) the number of hospital admissions for which

dementia was recorded as the principal or secondary diagnosis; iii) the number of times that a diagnosis of dementia was recorded in

our electronic health record data (regardless of whether the diagnosis was recorded in primary, secondary, or tertiary care); iv) the

predicted probability of dying due to dementia (i.e., a death with dementia recorded as the underlying cause on the death certiﬁcate)

during the follow-up period; and v) the predicted probability of dying from any cause during the follow-up period. We calculated the

predicted probability of death from any cause using a logistic regression model with death from any cause during the nine-year

follow-up period as outcome and age on September 1 2013 as well as each condition (as measured in the time period prior to

September 1 2013) that is part of the Charlson Comorbidity Index (except for AIDS, which is a condition that is suppressed in the

SAIL database for privacy reasons) as predictor variables.

The coefﬁcients were ﬁrst estimated using only patients who were inel-

igible for HZ vaccination based on their date of birth. The estimated model was then used to predict the risk of death for all patients

whilst imputing a ﬁxed age of 80 years. The predicted probability of deaths due to dementia was calculated using the same approach

except that we also included the total number of inpatient days spent in hospital (as part of admissions for which dementia was re-

corded as the principal or secondary reason) and the number of recordings of a diagnosis of dementia as additional predictors. To

maximize statistical power for detecting subgroup differences, we deﬁned subgroups for each dementia severity measure based on

whether individuals were above or below the median. When using our regression discontinuity approach, we compared both the ab-

solute and relative effects of HZ vaccination on deaths due to dementia between these subgroups. The relative effects were esti-

mated by dividing the absolute effect by the predicted value of the outcome just left (i.e., among those who were ineligible for HZ

vaccination when analyzing the effect of vaccination eligibility and among those who were ineligible for HZ vaccination and complied

with their eligibility assignment when analyzing the effect of vaccine receipt) of the September 2 1933 date-of-birth eligibility

threshold. The conﬁdence intervals and p-values for these relative effect estimates were calculated using the delta method.

Regression equations

Regression discontinuity

We used the following model to estimate the effect of being eligible for HZ vaccination on our outcomes:

= α + β

+ β

⋅ (WOB

− c

) + β

⋅ (WOB

− c

) + ϵ

; (Equation 1)

where Y

was a dichotomous variable indicating if an individual had the outcome, and D

was a dichotomous variable indicating eligi-

bility for HZ vaccination (i.e., D

was equal to one if an individual was born on or after September 2 1933). The term (WOB

− c

) and

the interaction term D

⋅(WOB

− c

) adjusted for how many weeks away from the September 2 1933 date-of-birth eligibility threshold

an individual was born. These terms ﬁtted two regression lines on either side of the September 2 1933 date-of-birth eligibility

threshold whereby the slope of these regression lines could differ on either side of the threshold. The coefﬁcient β

identiﬁed the effect

of being eligible for HZ vaccination on the outcome.

We used the following model to estimate the effect of receiving HZ vaccination on our outcomes:

= θ + γ

+ γ

⋅ (WOB

− c

) + γ

⋅ (WOB

− c

) + ε

; (Equation 2)

where V

was a dichotomous variable indicating if an individual received HZ vaccination and was instrumented by D

was the pre-

dicted probability of receiving HZ vaccination based on the estimation of Equation 1 with V

as the left-hand-side variable. γ

was the

effect of receiving HZ vaccination. θ was the constant and ε

an error term. All other variables were the same as in regression Equation

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1. Equation 2, thus, implemented a so-called fuzzy regression discontinuity (RD) design,

which adjusted the effect size for being

eligible for HZ vaccination by the size of the abrupt change in the probability of receiving HZ vaccination at the September 2 1933

date-of-birth eligibility threshold. As is common practice for fuzzy RD,

our fuzzy RD achieved this adjustment by using a dichoto-

mous variable that indicated whether or not an individual was eligible to receive HZ vaccination as an instrumental variable for actual

receipt of HZ vaccination. For Equations 1 and 2, we restricted the analysis to individuals who were born within the MSE-optimal

bandwidths around the threshold, applied triangular kernel weights, and reported p-values and 95% conﬁdence intervals based

on robust bias-corrected standard errors.

101

Difference-in-differences

As described in the STAR Methods section in the main manuscript, we implemented our DID approach by dividing our sample into

yearly birth cohorts centered around September 1, and then dividing each yearly birth cohort into a pre-September birth ‘‘season’’

(i.e., the six-months period of March 1 to August 31) and a post-September birth season (i.e., the six-months period from September

1 to February 28 of the succeeding year). Our DID approach relied on the assumption that in the absence of the date of birth-based

eligibility rule for HZ vaccination, the between-birth-season difference in the outcome would have been the same in the 1933/1934-

cohort as in the other yearly birth cohorts. To investigate the validity of this assumption, we estimated the between-birth-season dif-

ference in the outcome for each yearly birth cohort, whereby the difference in the 1932/33-cohort served as the reference group.

Speciﬁcally, we used the following model:

= θ +

∑

h∕=1932

(

⋅ C

)

+ η

+ ϵ

; (Equation 3)

where Y

was the outcome of patient i, and S

a dichotomous variable indicating that patient i was born in the post-September birth

season. C

indicated whether patient i belonged to birth cohort h, with h = 1926/27, 1927/28, …, 1931/32, and 1933/34. γ

identiﬁed

the between-birth-season difference of the yearly birth cohort h relative to the 1932/33-cohort. θ was the constant term, η

and η

indicated the birth month and birth cohort ﬁxed-effect, respectively. ϵ

was the error term. Figure S11 plots the estimates of γ

with

95% conﬁdence intervals by yearly birth cohort.

We used a two-stage least squares procedure to implement our DID approach. The ﬁrst stage estimated the change in the prob-

ability of receiving HZ vaccination due to the date of birth-based eligibility rule. We used the following model:

= θ + γS

⋅C

+ η

+ ϵ

; (Equation 4)

where V

was a dichotomous variable indicating whether patient i had received HZ vaccination, S

a dichotomous variable indicating

that patient i was born in the post-September birth season, and C

a dichotomous variable indicating that patient i was in the 1933/

1934 birth cohort. γ identiﬁed the change in the probability of receiving HZ vaccination as a result of the date of birth-based eligibility

rule. θ was a constant term and ϵ

was the error term. η

and η

were the birth month and cohort ﬁxed effect, respectively.

In the second stage, we estimated the effect of receipt of HZ vaccination on our outcomes. We used the following model:

= α + β

+ η

+ ε

; (Equation 5)

where Y

was the outcome of patient i, and

was the probability of receiving HZ vaccination as a result of the date of birth-based

eligibility rule as estimated from the ﬁrst-stage regression (4). The coefﬁcient β identiﬁed the effect of HZ vaccination receipt on our

outcome. θ; η

, and η

were the constant term, birth month, and yearly birth cohort (1926/1927, 1927/1928, …, 1933/1934) ﬁxed ef-

fect, respectively. ε

was the error term.

Heterogeneous treatment effect by gender

The difference in CACE by gender was estimated by running the following instrumental variable model:

= α + β

+ β

(WOB

− c

) + β

(WOB

− c

) + β

⋅ MALE

+ β

⋅ (WOB

− c

) ⋅ MALE

+ β

⋅ (WOB

− c

) ⋅ MALE

+ β

MALE

+ϵ

(Equation 6)

where Y

, D

, (WOB

− c

) and V

adopted the same deﬁnitions as in Equations 1 and 2. MALE

was a dichotomous variable indicating

if an individual’s gender was male. ϵ

was the error term. The coefﬁcient β

identiﬁes the gender difference in the effect of receipt of the

vaccine on the outcome. In estimating the coefﬁcients, V

and V

⋅MALE

were instrumented by D

and D

⋅MALE

. In line with our pri-

mary discontinuity models, we applied triangular weights to the regression along with the MSE-optimal bandwidth sizes from the

corresponding speciﬁcation excluding interaction terms by gender in our primary analyses.

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Supplemental ﬁgures

Indicators of preventive health services uptake

Leading causes of morbidity and mortality

Antihypertensive medication use

Breast cancer screening

Influenza vaccination

PPV vaccination

Statin use

Breast cancer

COPD

Colorectal cancer

Dementia

Diabetes mellitus

Falls

Ischemic heart disease

Lower back pain

Lower respiratory tract infection

Lung cancer

Mild cognitive impairment

Pancreatic cancer

Shingles

Stroke

0.7 ( −1.1, 2.5)

−0.5 ( −2.5, 1.5)

0.0 ( −1.5, 1.4)

−0.1 ( −2.0, 1.3)

0.8 ( −0.7, 2.7)

0.2 ( −0.7, 1.0)

0.0 ( −1.1, 1.3)

0.4 ( −0.1, 1.2)

0.5 ( −0.3, 1.4)

0.0 ( −1.5, 1.5)

0.4 ( −0.9, 2.0)

−0.7 ( −2.2, 0.4)

−0.9 ( −3.0, 0.9)

0.2 ( −1.7, 1.9)

0.1 ( −0.2, 0.3)

−0.2 ( −1.1, 0.4)

0.0 ( −0.1, 0.1)

0.1 ( −1.2, 1.4)

−0.2 ( −1.2, 0.8)

0.455

0.626

0.918

0.696

0.244

0.765

0.933

0.113

0.174

0.999

0.462

0.173

0.299

0.909

0.493

0.390

0.926

0.887

0.645

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−5.0 −2.5 0.0 2.5 5.0

Among patients without cognitive impairment at baseline

Indicators of preventive health services uptake

Leading causes of morbidity and mortality

Antihypertensive medication use

Breast cancer screening

Influenza vaccination

PPV vaccination

Statin use

Breast cancer

COPD

Colorectal cancer

Deaths due to dementia

Diabetes mellitus

Falls

Ischemic heart disease

Lower back pain

Lower respiratory tract infection

Lung cancer

Pancreatic cancer

Stroke

3.2 ( −5.2, 11.8)

6.5 ( −0.8, 16.8)

−0.4 ( −7.8, 7.0)

−1.2 ( −7.3, 4.5)

−1.9 ( −9.8, 5.2)

2.3 ( −0.7, 6.3)

0.4 ( −4.5, 5.1)

−0.3 ( −2.2, 1.8)

−5.2 (−17.7, 6.7)

−0.6 ( −7.2, 6.8)

−3.1 (−10.4, 4.4)

−8.5 (−15.8, −2.4)

1.2 ( −6.8, 10.5)

−4.3 (−12.1, 1.8)

0.5 ( −0.2, 1.3)

0.2 ( −0.1, 0.5)

0.8 ( −4.8, 7.3)

0.447

0.076

0.916

0.633

0.547

0.121

0.888

0.859

0.375

0.960

0.424

0.008

0.680

0.148

0.130

0.173

0.691

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−20 −10 0 10 20

Among patients living with dementia at baseline

Figure S1. Baseline balance checks using diagnoses of the ten most common causes of DALYs and mortality among adults aged 70+ years

in Wales, as well as indicators of preventive health services uptake, related to Figure 1

Baseline refers to the start date of the HZ vaccination program (i.e., September 1, 2013). We used diagnoses of the ten most common causes of disability-

adjusted life years (DALYs) and mortality among the age group 70+ years in Wales, as estimated by the 2019 Global Burden of Disease study.

Statin use was

deﬁned as a new or repeat prescription of a statin in the 12 months preceding September 1, 2013. PPV vaccination was deﬁned as receipt of the PPV vaccine as

an adult at any time prior to September 1, 2013. Inﬂuenza vaccination was deﬁned as receipt of the inﬂuenza vaccine in the 12 months preceding September 1,

2013. Breast cancer screening was deﬁned as the proportion of women with a record of referral to, attendance at, or a report from breast cancer screening or

mammography at any time prior to September 1, 2013. Antihypertensive medication use was deﬁned as a new or repeat prescription of an antihypertensive drug

in the 12 months preceding September 1, 2013. The study cohorts for the baseline balance checks for MCI and dementia did not exclude individuals with any

record of cognitive impairment prior to September 1, 2013. Similarly, the study cohort for the baseline balance check for deaths due to dementia was not

restricted to individuals who were alive on September 1, 2013. For all other baseline balance checks, the study cohort was deﬁned as detailed in the STAR

Methods. Dots show the point estimate and horizontal bars the 95% CI. The codes used to deﬁne each condition are listed in Data S1.

Abbreviations are as follows: CI, conﬁdence interval; COPD, chronic obstructive pulmonary disease; PPV, pneumococcal polysaccharide vaccine.

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Follow−up period (years)

−0.1 (−0.6, 0.1)

−0.3 (−1.4, 0.2)

−0.5 (−1.1, −0.1)

−1.3 (−2.8, −0.4)

−0.6 (−1.3, −0.1)

−1.6 (−3.5, −0.5)

−1.1 (−2.1, −0.4)

−2.0 (−4.4, −0.8)

−0.8 (−1.9, 0.0)

−1.6 (−4.1, 0.0)

−0.8 (−2.0, 0.0)

−1.9 (−4.6, −0.2)

−1.2 (−2.4, −0.3)

−2.5 (−5.5, −0.8)

−1.3 (−2.5, −0.4)

−2.8 (−5.8, −0.8)

−1.5 (−2.9, −0.5)

−3.1 (−6.2, −1.0)

0.253

0.157

0.026

0.009

0.025

0.008

0.005

0.061

0.055

0.041

0.034

0.010

0.009

0.008

0.009

0.006

0.007

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−10.0 −7.5 −5.0 −2.5 0.0 2.5

Effect of vaccination eligibility

Effect of vaccine receipt

Effect on MCI

Follow−up period (years)

−2.6 (−7.1, 1.4)

−8.9 (−24.2, 5.1)

−2.7 (−9.2, 3.7)

−9.4 (−31.3, 13.3)

−3.4 (−10.7, 2.8)

−12.0 (−37.0, 10.1)

−3.9 (−11.3, 3.8)

−13.6 (−38.6, 13.9)

−6.6 (−15.3, 1.9)

−22.8 (−52.1, 7.6)

−8.9 (−19.1, −1.0)

−30.7 (−65.4, −2.1)

−8.2 (−18.5, −0.2)

−28.4 (−63.3, 0.5)

−7.7 (−17.6, 0.2)

−26.7 (−59.9, 2.1)

−8.5 (−18.5, −0.6)

−29.5 (−62.9, −0.6)

0.183

0.200

0.407

0.430

0.249

0.264

0.334

0.356

0.125

0.145

0.029

0.036

0.044

0.054

0.056

0.068

0.036

0.046

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−75 −50 −25 0 25

Effect of vaccination eligibility

Effect of vaccine receipt

Effect on deaths due to dementia

Figure S2. The effect of HZ vaccination eligibility and receipt on our outcomes across different lengths of follow-up, related to Figure 2

Dots or triangles show the point estimate and horizontal bars the 95% CI.

Abbreviations are as follows: MCI, mild cognitive impairment; CI, conﬁdence interval.

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Other checks

Alternative outcome definition

Grace−period (months)

Bandwidth choice (as x−times the MSE−optimal bandwidth)

Accounting for staggered roll−outAccounting for staggered roll−out

Controlling for health service utilizationControlling for health service utilization

Quadratic fitQuadratic fit

Restricting to frequent GP visitorsRestricting to frequent GP visitors

MCI not followed by dementia within 3 monthsMCI not followed by dementia within 3 months

MCI not followed by dementia within 6 monthsMCI not followed by dementia within 6 months

0.50.5

0.750.75

1.251.25

1.51.5

1.751.75

2 2

−1.5 ( −2.8, −0.5)

−3.3 ( −6.8, −0.5)

−1.5 ( −2.8, −0.5)

−3.1 ( −6.1, −1.0)

−1.7 ( −3.3, −0.6)

−3.5 ( −6.7, −1.1)

−1.3 ( −2.8, −0.3)

−2.6 ( −5.7, −0.4)

−1.4 ( −2.8, −0.5)

−3.0 ( −5.9, −1.1)

−1.3 ( −2.6, −0.4)

−2.8 ( −5.6, −1.0)

−1.5 ( −2.9, −0.5)

−3.1 ( −6.2, −1.0)

−1.5 ( −2.9, −0.5)

−3.1 ( −6.3, −1.0)

−1.5 ( −3.0, −0.5)

−3.3 ( −6.5, −1.2)

−1.7 ( −3.4, 0.0)

−3.7 ( −8.3, −0.1)

−1.4 ( −2.9, −0.2)

−3.1 ( −6.5, −0.2)

−1.5 ( −2.9, −0.5)

−3.1 ( −6.2, −1.0)

−1.4 ( −2.6, −0.5)

−2.9 ( −5.7, −1.0)

−1.1 ( −2.3, −0.3)

−2.4 ( −4.9, −0.7)

−1.0 ( −2.0, −0.2)

−2.1 ( −4.5, −0.5)

−0.9 ( −1.7, −0.1)

−1.9 ( −4.0, −0.3)

0.005

0.022

0.006

0.007

0.017

0.022

0.006

0.005

0.006

0.004

0.006

0.007

0.006

0.007

0.005

0.004

0.056

0.046

0.027

0.036

0.006

0.007

0.005

0.009

0.011

0.017

0.014

0.033

0.026

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−10.0 −7.5 −5.0 −2.5 0.0 2.5

Effect of v

accination eligibility

Effect of vaccine receipt

Effect on MCI

Other checks

Grace−period (months)

Ban

dwidth choice (as x−times the MSE−optimal bandwidth)

Accounting for staggered roll−outAccounting for staggered roll−out

Adjusting for baseline IHD diagnosisAdjusting for baseline IHD diagnosis

Quadratic fitQuadratic fit

0.50.5

0.750.75

1.251.25

1.51.5

1.751.75

2 2

−8.1 ( −18.0, −0.3)

−31.3 ( −69.2, −0.2)

−7.7 ( −13.7, −1.7)

−27.1 ( −48.2, −6.0)

−8.9 ( −19.6, 0.4)

−29.6 ( −64.6, 2.7)

−8.5 ( −18.5, −0.6)

−29.5 ( −62.9, −0.6)

−8.1 ( −17.8, −0.2)

−28.0 ( −60.7, 1.0)

−8.0 ( −17.8, −0.1)

−27.9 ( −60.7, 1.4)

−8.4 ( −21.1, 4.7)

−29.3 ( −73.9, 16.6)

−9.0 ( −20.5, 0.2)

−32.2 ( −73.1, 1.5)

−8.5 ( −18.5, −0.6)

−29.5 ( −62.9, −0.6)

−7.0 ( −15.9, 0.0)

−24.7 ( −55.5, 1.0)

−6.4 ( −14.7, −0.2)

−23.5 ( −54.2, −0.4)

−5.8 ( −13.9, −0.5)

−22.0 ( −53.1, −2.2)

−5.4 ( −12.9, −0.4)

−20.6 ( −50.1, −2.0)

0.042

0.048

0.012

0.061

0.072

0.036

0.046

0.045

0.058

0.048

0.061

0.212

0.215

0.055

0.060

0.036

0.046

0.051

0.059

0.043

0.047

0.034

0.033

0.036

0.033

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−100 −75 −50 −25 0 25

Effect of vaccination eligibility

Effect of vaccine receipt

Effect on deaths due to dementia

(legend on next page)

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Figure S3. Robustness checks for the effect of HZ vaccination eligibility and receipt on our outcomes, related to Figure 2

Dots or triangles show the point estimate and horizontal bars the 95% CI. With ‘‘grace periods,’’ we refer to time periods since the index date after which follow-up

time is considered to begin to allow for the time needed for a full immune response to develop after vaccine administration. Frequent GP visitors were deﬁned as

patients who had made at least one visit to their primary care provider during each of the 5 years preceding the start of the HZ vaccination program. The health

service utilization indicators that were used when controlling for health service utilization were the number of primary care visits, outpatient visits, hospital ad-

missions, and inﬂuenza vaccinations received during our 9-year follow-up period. As described in detail in the STAR Methods, when accounting for the staggered

roll-out of the program, we adjusted the follow-up period to begin for each individual on the date on which they ﬁrst became eligible for HZ vaccination (instead of

starting the follow-up period for all individuals on September 1, 2013). We added cohort ﬁxed effects to these analyses to control for between-cohort differences

in the date at which the follow-up window started. That is, we deﬁned one cohort ﬁxed effect for ineligible individuals and the ﬁrst catch-up cohort and included

additional cohort ﬁxed effects for each group of patients who became eligible at the same time.

Abbreviations are as follows: MCI, mild cognitive impairment; CI, conﬁdence interval; MSE, mean squared error; GP, general practitioner; IHD, ischemic heart

disease.

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Eligibility cutoff with a 6−

year follow−up

1930−09−021930−09−02

1931−09−021931−09−02

1932−09−021932−09−02

1933−09−021933−09−02

1934−09−021934−09−02

1935−09−021935−09−02

1936−09−021936−09−02

−0.6 ( −2.2, 0.6)

2.2 ( −5.4, 10.4)

0.1 ( −0.9, 1.3)

3.4 ( −4.9, 11.8)

0.4 ( −0.5, 1.3)

3.8 ( −4.9, 11.9)

−0.8 ( −2.0, 0.0)

−8.8 (−19.1, −1.0)

0.2 ( −0.6, 1.2)

−0.7 ( −7.4, 5.6)

−0.2 ( −1.0, 0.7)

0.8 ( −7.8, 8.1)

0.3 ( −0.5, 1.4)

0.2 ( −7.5, 8.5)

0.252

0.537

0.704

0.424

0.345

0.412

0.041

0.029

0.532

0.783

0.721

0.965

0.363

0.902

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−20 −10

MCI

Deaths due to dementia

Figure S4. The September 2 date-of-birth threshold only had a signiﬁcant effect on our outcomes in the birth year (1933) that was used by the

herpes zoster vaccination program as eligibility criterion, related to Figure 2

Diamonds or crosses show the point estimate and horizontal bars the 95% CI. New diagnoses of MCI were analyzed among a study cohort of patients who did not

have any record of cognitive impairment prior to the start of the follow-up period. Deaths due to dementia were analyzed among a study cohort of patients who

had received a diagnosis of dementia prior to the start of the follow-up period. We used a 6-year instead of a 9-year follow-up period in this analysis to allow for the

same length of follow-up for all comparisons.

Abbreviations are as follows: CI, conﬁdence interval; MCI, mild cognitive impairment.

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Other checks

Alternative outcome definition

Grace−period (months)

Ban

dwidth choice (as x−times the MSE−optimal bandwidth)

Accounting for staggered roll−outAccounting for staggered roll−out

Controlling for health service utilizationControlling for health service utilization

Quadratic fitQuadratic fit

Restricting to frequent GP visitorsRestricting to frequent GP visitors

MCI not followed by dementia within 3 monthsMCI not followed by dementia within 3 months

MCI not followed by dementia within 6 monthsMCI not followed by dementia within 6 months

0.50.5

0.750.75

1.251.25

1.51.5

1.751.75

2 2

−2.4 ( −4.4, −1.1)

−5.4 (−10.3, −2.5)

−2.4 ( −4.3, −1.2)

−5.1 ( −9.7, −2.6)

−2.8 ( −4.8, −1.2)

−6.1 (−10.6, −2.5)

−2.4 ( −4.5, −0.9)

−4.3 ( −9.0, −1.8)

−2.5 ( −4.5, −1.2)

−5.1 ( −9.6, −2.8)

−2.4 ( −4.2, −1.1)

−4.8 ( −9.1, −2.6)

−2.5 ( −4.5, −1.1)

−5.1 ( −9.8, −2.6)

−2.4 ( −4.4, −1.0)

−4.9 ( −9.6, −2.3)

−2.5 ( −4.6, −1.1)

−5.3 (−10.1, −2.7)

−2.7 ( −5.2, −0.3)

−5.9 (−11.9, −1.0)

−2.6 ( −4.8, −0.9)

−5.6 (−10.7, −2.3)

−2.5 ( −4.5, −1.1)

−5.1 ( −9.8, −2.6)

−2.3 ( −4.1, −1.1)

−4.3 ( −8.8, −2.3)

−2.0 ( −3.7, −1.0)

−3.6 ( −8.0, −2.0)

−1.7 ( −3.3, −0.8)

−3.1 ( −7.1, −1.5)

−1.5 ( −2.9, −0.5)

−2.5 ( −6.1, −0.9)

0.001

<0.001

0.001

0.004

<0.001

0.001

<0.001

0.002

0.001

<0.001

0.026

0.021

0.004

0.003

0.001

<0.001

0.001

0.002

0.003

0.004

0.008

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−15 −10 −5 0 5

Effect of vaccination eligibility

Effect of vaccine receipt

Effect on MCI among women

Other checks

Grace−period (months)

Ban

dwidth choice (as x−times the MSE−optimal bandwidth)

Accounting for staggered roll−outAccounting for staggered roll−out

Adjusting for baseline IHD diagnosisAdjusting for baseline IHD diagnosis

Quadratic fitQuadratic fit

0.50.5

0.750.75

1.251.25

1.51.5

1.751.75

2 2

−12.7 ( −24.8, −2.3)

−51.7 (−100.5, −6.1)

−14.4 ( −23.7, −5.1)

−60.7 ( −98.8, −22.6)

−14.0 ( −27.5, −1.8)

−50.5 ( −98.6, −3.4)

−13.9 ( −26.3, −3.4)

−52.3 ( −97.9, −9.2)

−14.5 ( −26.7, −4.2)

−55.0 (−100.3, −11.5)

−13.7 ( −25.7, −3.4)

−52.0 ( −96.7, −8.7)

−14.2 ( −30.2, 2.8)

−52.3 (−111.9, 13.1)

−15.2 ( −30.4, −3.8)

−57.9 (−117.0, −11.7)

−13.9 ( −26.3, −3.4)

−52.3 ( −97.9, −9.2)

−11.8 ( −22.8, −2.5)

−45.5 ( −86.7, −7.0)

−11.6 ( −22.2, −3.8)

−46.5 ( −89.0, −13.1)

−11.3 ( −21.5, −4.5)

−46.4 ( −88.7, −17.1)

−10.9 ( −20.2, −4.3)

−45.4 ( −85.0, −17.0)

0.018

0.027

0.002

0.026

0.036

0.011

0.018

0.007

0.014

0.010

0.019

0.103

0.121

0.012

0.017

0.011

0.018

0.015

0.021

0.006

0.008

0.003

0.004

0.002

0.003

Effect size, 95% CI

(percentage points)

Effect size, 95% CI

(percentage points)

−120 −80 −40 0

Effect of vaccination eligibility

Effect of vaccine receipt

Effect on deaths due to dementia among women

(legend on next page)

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Figure S5. Robustness checks for the effect of HZ vaccination eligibility and receipt on our outcomes among women only, related to Figure 4

Dots or triangles show the point estimate and horizontal bars the 95% CI. With grace periods, we refer to time periods since the index date after which follow-up